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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATXN3
All Species:
17.27
Human Site:
S260
Identified Species:
29.23
UniProt:
P54252
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54252
NP_001121168.1
364
41781
S260
I
Q
L
S
M
Q
G
S
S
R
N
I
S
Q
D
Chimpanzee
Pan troglodytes
XP_001146724
368
42242
S260
I
Q
L
S
M
Q
G
S
S
R
N
I
S
Q
D
Rhesus Macaque
Macaca mulatta
XP_001116022
352
40079
S252
I
Q
L
S
M
Q
G
S
S
R
N
I
S
Q
D
Dog
Lupus familis
XP_537352
301
34778
N216
L
E
R
V
L
E
A
N
D
G
S
G
M
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVD2
355
40515
S260
I
Q
L
S
M
Q
G
S
S
R
S
M
C
E
N
Rat
Rattus norvegicus
O35815
355
40428
S260
I
Q
L
S
M
Q
G
S
S
R
G
M
C
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507271
358
40934
A267
M
Q
G
S
H
R
N
A
S
Q
D
R
P
Q
T
Chicken
Gallus gallus
Q9W689
363
41590
L272
Q
S
E
F
S
N
S
L
P
Q
N
A
S
Q
P
Frog
Xenopus laevis
NP_001085659
316
35907
G223
I
Q
L
S
M
Q
G
G
N
Q
S
E
F
T
E
Zebra Danio
Brachydanio rerio
NP_957398
266
30028
K181
E
D
E
E
E
L
R
K
A
L
A
L
S
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623341
340
38556
N238
I
P
I
K
I
E
K
N
D
E
E
D
D
E
N
Nematode Worm
Caenorhab. elegans
O17850
317
35845
A230
K
D
L
A
I
A
F
A
M
S
M
E
T
K
D
Sea Urchin
Strong. purpuratus
XP_786733
388
42119
E292
D
E
L
R
R
K
R
E
A
F
F
N
R
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M391
280
30674
W195
A
S
N
S
F
G
Q
W
L
S
P
E
D
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
88.7
79.1
N.A.
80.2
80.4
N.A.
78
70.5
52.2
50.5
N.A.
N.A.
42.8
31.3
38.4
Protein Similarity:
100
97.8
90.1
80.7
N.A.
85.4
85.7
N.A.
85.1
79.9
64.8
61.8
N.A.
N.A.
59.6
48.6
56.4
P-Site Identity:
100
100
100
6.6
N.A.
66.6
73.3
N.A.
26.6
20
46.6
6.6
N.A.
N.A.
6.6
13.3
13.3
P-Site Similarity:
100
100
100
46.6
N.A.
93.3
86.6
N.A.
60
26.6
73.3
26.6
N.A.
N.A.
46.6
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
8
15
15
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% C
% Asp:
8
15
0
0
0
0
0
0
15
0
8
8
15
0
43
% D
% Glu:
8
15
15
8
8
15
0
8
0
8
8
22
0
22
15
% E
% Phe:
0
0
0
8
8
0
8
0
0
8
8
0
8
0
0
% F
% Gly:
0
0
8
0
0
8
43
8
0
8
8
8
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
8
0
15
0
0
0
0
0
0
22
0
0
0
% I
% Lys:
8
0
0
8
0
8
8
8
0
0
0
0
0
8
0
% K
% Leu:
8
0
58
0
8
8
0
8
8
8
0
8
0
8
0
% L
% Met:
8
0
0
0
43
0
0
0
8
0
8
15
8
0
0
% M
% Asn:
0
0
8
0
0
8
8
15
8
0
29
8
0
0
22
% N
% Pro:
0
8
0
0
0
0
0
0
8
0
8
0
8
0
8
% P
% Gln:
8
50
0
0
0
43
8
0
0
22
0
0
0
43
8
% Q
% Arg:
0
0
8
8
8
8
15
0
0
36
0
8
8
8
0
% R
% Ser:
0
15
0
58
8
0
8
36
43
15
22
0
36
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _